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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
11.5 DPC

19 matching records from 19 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Bmp4  bone morphogenetic protein 4   (Synonyms: Bmp2b, Bmp2b1, Bmp2b-1, Bmp-4)
Results  Reference
1J:145964 Chandler KJ, Chandler RL, Mortlock DP, Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter. Dev Biol. 2009 Mar 15;327(2):590-602
1*J:206541 Engelhard C, Sarsfield S, Merte J, Wang Q, Li P, Beppu H, Kolodkin AL, Sucov HM, Ginty DD, MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons. Elife. 2013;2:e01160
1J:134120 Feng JQ, Zhang J, Tan X, Lu Y, Guo D, Harris SE, Identification of cis-DNA regions controlling Bmp4 expression during tooth morphogenesis in vivo. J Dent Res. 2002 Jan;81(1):6-10
1J:108516 Goldman DC, Hackenmiller R, Nakayama T, Sopory S, Wong C, Kulessa H, Christian JL, Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity. Development. 2006 May;133(10):1933-42
1J:176247 Gordon J, Manley NR, Mechanisms of thymus organogenesis and morphogenesis. Development. 2011 Sep;138(18):3865-78
1*J:82630 Hall JM, Bell ML, Finger TE, Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae. Dev Biol. 2003 Mar 15;255(2):263-77
1J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86
1*J:159629 Jang CW, Gao L, Dickinson ME, Behringer RR, Bmp4-directed nuclear cyan fluorescent protein provides a tool for live imaging and reveals cellular resolution of Bmp4 expression patterns during embryogenesis. Int J Dev Biol. 2010;54(5):931-8
1J:86001 Jiao K, Kulessa H, Tompkins K, Zhou Y, Batts L, Baldwin HS, Hogan BL, An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 2003 Oct 1;17(19):2362-7
1J:187837 Jumlongras D, Lachke SA, O'Connell DJ, Aboukhalil A, Li X, Choe SE, Ho JW, Turbe-Doan A, Robertson EA, Olsen BR, Bulyk ML, Amendt BA, Maas RL, An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud. PLoS One. 2012;7(6):e38568
1J:142133 Li Y, Gordon J, Manley NR, Litingtung Y, Chiang C, Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis. Dev Biol. 2008 Oct 1;322(1):145-55
1*J:121311 Liu Z, Yu S, Manley NR, Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol. 2007 May 1;305(1):333-46
1J:122530 Michos O, Goncalves A, Lopez-Rios J, Tiecke E, Naillat F, Beier K, Galli A, Vainio S, Zeller R, Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development. 2007 Jul;134(13):2397-405
1J:144308 Ovchinnikov DA, Selever J, Wang Y, Chen YT, Mishina Y, Martin JF, Behringer RR, BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning. Dev Biol. 2006 Jul 1;295(1):103-15
1*J:112219 Patel SR, Gordon J, Mahbub F, Blackburn CC, Manley NR, Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expr Patterns. 2006 Dec;6(8):794-9
1J:71204 Rossi JM, Dunn NR, Hogan BL, Zaret KS, Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev. 2001 Aug 1;15(15):1998-2009
1J:213855 Tilak A, Nelsen SM, Kim HS, Donley N, McKnite A, Lee H, Christian JL, Simultaneous rather than ordered cleavage of two sites within the BMP4 prodomain leads to loss of ligand in mice. Development. 2014 Aug;141(15):3062-71
1*J:83697 Weaver M, Batts L, Hogan BL, Tissue interactions pattern the mesenchyme of the embryonic mouse lung. Dev Biol. 2003 Jun 1;258(1):169-84
1*J:55441 Weaver M, Yingling JM, Dunn NR, Bellusci S, Hogan BL, Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development. 1999 Sep;126(18):4005-15

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory